Andrew J Brenner Selected Research

4- (1- (5- (3,4- dimethyl- 1H- pyrazol- 5- yl)- 2,4- dimethylbenzoyl)azetidin- 3- yl)benzonitrile

6/2021

FASN inhibition as a potential treatment for endocrine-resistant breast cancer.

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Andrew J Brenner Research Topics

Disease

25	Neoplasms (Cancer) 01/2022 - 09/2011
12	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2012
8	Breast Neoplasms (Breast Cancer) 06/2021 - 01/2013
8	Glioma (Gliomas) 01/2021 - 04/2012
5	Obesity 01/2015 - 01/2013
4	Brain Neoplasms (Brain Tumor) 01/2020 - 04/2012
3	Hypoxia (Hypoxemia) 01/2021 - 01/2016
2	Triple Negative Breast Neoplasms 10/2021 - 01/2021
2	Inflammation (Inflammations) 01/2020 - 08/2014
2	Neoplasm Metastasis (Metastasis) 08/2019 - 07/2013
2	Melanoma (Melanoma, Malignant) 09/2016 - 03/2015
2	Head and Neck Neoplasms (Head and Neck Cancer) 09/2016 - 03/2015
2	Carcinogenesis 01/2012 - 09/2011
1	Ependymoma 01/2022
1	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2020
1	Sudden Infant Death (SID) 01/2020
1	Ductal Carcinoma 01/2020
1	Meningeal Carcinomatosis 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2019
1	Adenocarcinoma of Lung 12/2019
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 12/2019
1	Disease Progression 11/2017

Drug/Important Bio-Agent (IBA)

5	Estrogen ReceptorsIBA 06/2021 - 01/2013
4	Pharmaceutical PreparationsIBA 01/2020 - 08/2014
3	EnzymesIBA 06/2021 - 01/2013
3	Estrogen Receptor betaIBA 01/2021 - 01/2015
3	Bevacizumab (Avastin)FDA Link 01/2021 - 01/2020
2	Histone Deacetylase InhibitorsIBA 10/2021 - 01/2021
2	TH 302IBA 01/2021 - 01/2021
2	Rhenium-186IBA 01/2021 - 04/2012
2	Histone DemethylasesIBA 01/2021 - 01/2013
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2019
2	ProdrugsIBA 01/2021 - 01/2021
2	MicroRNAs (MicroRNA)IBA 01/2020 - 09/2011
2	Everolimus FDA Link 01/2020 - 06/2013
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 09/2011
2	VaccinesIBA 01/2018 - 01/2018
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2015 - 08/2014
2	Estrogen Receptor alphaIBA 01/2015 - 01/2013
2	Aromatase (CYP19)IBA 01/2015 - 08/2014
2	Dinoprostone (PGE2)FDA Link 01/2015 - 08/2014
2	Radioisotopes (Radionuclides)IBA 09/2014 - 04/2012
2	LuciferasesIBA 04/2012 - 09/2011
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2012 - 09/2011
1	Mucin-1 (CA 15-3 Antigen)IBA 01/2022
1	SynaptophysinIBA 01/2022
1	4- (1- (5- (3,4- dimethyl- 1H- pyrazol- 5- yl)- 2,4- dimethylbenzoyl)azetidin- 3- yl)benzonitrileIBA 06/2021
1	LipidsIBA 06/2021
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 06/2021
1	Tamoxifen FDA LinkGeneric 06/2021
1	fluoromisonidazoleIBA 01/2021
1	erteberelIBA 01/2021
1	PanobinostatIBA 01/2021
1	Alkylating AgentsIBA 01/2021
1	isophosphamide mustard (IPAM)IBA 01/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	Doxycycline (Periostat)FDA LinkGeneric 01/2021
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2020
1	sacituzumab govitecanIBA 01/2020
1	7-ethyl-10-hydroxycamptothecin beta-glucuronideIBA 01/2020
1	paclitaxel-Angiopep-2 conjugateIBA 01/2020
1	Irinotecan (Camptosar)FDA LinkGeneric 01/2020
1	IsotopesIBA 01/2020
1	Leucine (L-Leucine)FDA Link 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Proline (L-Proline)FDA Link 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Glutamic Acid (Glutamate)FDA Link 01/2020
1	Immunoconjugates (Immunoconjugate)IBA 01/2020
1	Sirolimus (Rapamycin)FDA Link 01/2020
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2020
1	B7-H1 AntigenIBA 12/2019
1	LigandsIBA 08/2019
1	OSM-LIF ReceptorsIBA 08/2019
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 05/2019
1	CateninsIBA 05/2019
1	ThuliumIBA 01/2019
1	Contrast MediaIBA 01/2019
1	Temozolomide (Temodar)FDA LinkGeneric 01/2018
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2017
1	crinineIBA 09/2016
1	Amaryllidaceae AlkaloidsIBA 09/2016
1	5,10b-ethanophenanthridineIBA 09/2016
1	AlkaloidsIBA 09/2016
1	AminesIBA 10/2015
1	ophiobolin AIBA 10/2015
1	Antineoplastic Agents (Antineoplastics)IBA 03/2015
1	AcidsIBA 03/2015
1	Interleukin-6 (Interleukin 6)IBA 01/2015
1	ProstaglandinsIBA 08/2014

Therapy/Procedure

14	Therapeutics 06/2021 - 01/2013
3	Drug Therapy (Chemotherapy) 01/2021 - 06/2011
2	Intravenous Administration 01/2020 - 09/2014
2	Aftercare (After-Treatment) 07/2013 - 04/2012
1	Lasers (Laser) 01/2019
1	Craniotomy 01/2019
1	Radiotherapy 01/2018
1	Premedication 01/2017
1	Precision Medicine 09/2014